NASS Research Grant Winner Abstracts Presented at NASS 2024

The following abstracts are from NASS Research Grant winners that presented their completed research findings at the 2024 Annual Meeting. Topics include reversing disc degeneration, detecting residual disease in chordoma patients using personalized blood biomarkers, developing a liquid biopsy for spinal cord compression, and analyzing force-dependent molecular mechanisms in degenerative spinal disease.

On-chip Intervertebral Disc-Macrophage Crosstalk: Unraveling a Dynamic Immunomodulatory Strategy for Disc Degeneration

Li Xiao, PhD; Yuan Xing, PhD; Yi Zhang, MD; Li Jin, PhD; Xudong Li, MD, PhD

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ROCK-dependent Mechanotransduction of Macroscale Forces Drives Fibrosis in Degenerative Spinal Disease

Ganesh M. Shankar, MD, PhD; Muhamed Hadzipasic, MD, PhD; Margaret S. Sten, BS; John H. Shin, MD; Ali Kiapour, PhD; Alan J. Grodzinsky, PhD; Hadi T. Nia, PhD

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Development of a Liquid Biopsy for Spinal Cord Compression

Tej D. Azad, MD, MS; Nicholas Theodore, MD, MS; Kathleen R. Ran, AB; Chetan Bettegowda, MD, PhD

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Tracking Chordoma Disease Progression and Recurrence through Circulating Tumor DNA (ctDNA) in Patient Plasma

Raphaele Charest-Morin, MD; Landon Hansen, MD PhD; Stephen Yip, MD, PhD; Rory Goodwin, MD, PhD; Nicolas Dea, MD, MSc; Chetan Bettegowda, MD, PhD

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