Literature Review
Correlation of Kidney Dysfunction on Outcomes Following ACDF Procedures

Rachel X. Shi, MS
Yale School of Medicine New Haven, CT

Jonathan N. Grauer, MD
Yale School of Medicine New Haven, CT
Article Reviewed Hendrix, C. G., Goheer, H. E., Newcomb, A. H., & Carmouche, J. J. (2024). Advanced chronic kidney disease increases complications in anterior cervical discectomies with fusions: An analysis of 75,508 patients. North American Spine Society Journal, 19, 100331. https://doi.org/10.1016/j.xnsj.2024.100331 Commentary The current review assesses a study by Hendrix et al published in North American Spine Society Journal (NASSJ). This retrospective study examined the correlation of kidney dysfunction on perioperative outcomes following anterior cervical discectomy and fusion (ACDF) procedures.
The study was conducted using data from the 2011-2021 American College of Surgeons National Surgical Quality Improvement Program (ACS-NSQIP) database. ACDF procedures were identified based on Current Procedural Terminology codes. Exclusion criteria were patients missing preoperative serum creatinine values and/or sex.
Key Takeaways
- This retrospective study assessed the correlation of kidney dysfunction on perioperative outcomes following anterior cervical discectomy and fusion (ACDF) procedures.
- Higher grades of chronic kidney disease (CKD) were associated with higher rates of perioperative complications.
- Lower grades of CKD were not associated with an increased risk of perioperative complications.